The TELL automatic sample changer for macromolecular crystallography
نویسندگان
چکیده
منابع مشابه
FlexED8: the first member of a fast and flexible sample-changer family for macromolecular crystallography
Automated sample changers are now standard equipment for modern macromolecular crystallography synchrotron beamlines. Nevertheless, most are only compatible with a single type of sample holder and puck. Recent work aimed at reducing sample-handling efforts and crystal-alignment times at beamlines has resulted in a new generation of compact and precise sample holders for cryocrystallography: min...
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Automation of the mounting of cryocooled samples is now a feature of the majority of beamlines dedicated to macromolecular crystallography (MX). Robotic sample changers have been developed over many years, with the latest designs increasing capacity, reliability and speed. Here, the development of a new sample changer deployed at the ESRF beamline MASSIF-1 (ID30A-1), based on an industrial six-...
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A standard sample holder and vial for cryocooled macromolecular crystals has been defined for use with robotic sample changers. This SPINE standard sample holder is a modified version, with added features and specifications, of sample holders in common use. In particular, the SPINE standard meets the precision required for automatic sample exchange and includes a cap that is identified by a two...
متن کاملTowards a compact and precise sample holder for macromolecular crystallography
Most of the sample holders currently used in macromolecular crystallography offer limited storage density and poor initial crystal-positioning precision upon mounting on a goniometer. This has now become a limiting factor at high-throughput beamlines, where data collection can be performed in a matter of seconds. Furthermore, this lack of precision limits the potential benefits emerging from au...
متن کاملStrategies for macromolecular synchrotron crystallography.
Introduction During the past ten years the rate of protein structure determination by X-ray crystallography has risen about tenfold [1]. The use of synchrotron radiation was instrumental for this growth and the fraction of the results obtained this way increased from 28% in 1990 to 80% in 1999 (Figure 1). There are 52 synchrotron stations worldwide used for macromolecular crystallography, and t...
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ژورنال
عنوان ژورنال: Journal of Synchrotron Radiation
سال: 2020
ISSN: 1600-5775
DOI: 10.1107/s1600577520002416